EUTHYROX 50mcg | LEVOTHYROXINE 50mcg – 30 Tabs


Levothyroxine is a thyroid hormone used as replacement therapy in the treatment of hypothyroidism in Kenya. It is given in conditions such as diffuse non-toxic goitre and Hashimoto’s thyroiditis to suppress the secretion of thyroid-stimulating hormone (TSH) and hence prevent or reverse enlargement of the thyroid gland. Levothyroxine is also used to suppress TSH production in the treatment of thyroid carcinoma and as a diagnostic agent for the differential diagnosis of hyperthyroidism. It is given with antithyroid drugs in the blocking-replacement regimen for the management of hyperthyroidism. Its absorption can be irregular and it is probably best taken on an empty stomach, usually before breakfast.

SKU: EP1930 Category:


Adverse Effects and Treatment

The adverse effects of levothyroxine in Kenya are generally associated with excessive dosage and correspond to symptoms of hyperthyroidism. They may include tachycardia, palpitations, cardiac arrhythmias, increase in blood pressure, anginal pain, headache, restlessness, excitability, insomnia, tremors, muscle weakness and cramps, heat intolerance, sweating, flushing, fever, weight loss, menstrual irregularities, diarrhoea, and vomiting. These adverse reactions usually disappear after dosage reduction or temporary withdrawal of treatment. Thyroid storm has occasionally been reported after massive or chronic intoxication and convulsions, cardiac arrhythmias, heart failure, coma, and death have occurred.

In acute overdosage, activated charcoal may be used to reduce gastrointestinal absorption if ingestion has occurred within 1 hour. Treatment is usually symptomatic and supportive; propranolol may be useful in controlling the symptoms of sympathetic overactivity. Levothyroxine overdosage requires an extended follow-up period as symptoms may be delayed for up to 6 days due to the gradual peripheral conversion of levothyroxine to tri-iodothyronine. UK licensed product information has suggested that glucocorticoids may be given to inhibit this conversion.


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