NEBI AM (NEBIVOLOL 5MG/AMLODIPINE 5MG) – 30 TABS are used in the management of Hypertension/High Blood Pressure in Kenya. This is a condition characterized by a raise in blood pressure to levels of above 140/90mmHG. This product should not be used in pregnancy, unless with proper guidance from a qualified physician. You can buy it online in Kenya through ePharmacy Kenya Online Chemist.

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Uses and Administration

Nebivolol is used in the management of hypertension in Kenya. It is given by mouth and the usual dose is 5 mg of nebivolol daily. An initial dose of 2.5 mg daily is used in the elderly and in patients with renal impairment. Amlodipine is a calcium-channel blocker. It is used in the management of hypertension and angina pectoris, by reducing the activities of the heart.

Common Adverse Effects of Nebivolol/Amlodipine

Nebivolol is generally well tolerated and most adverse effects are mild. The most frequent and serious adverse effects reported in Kenya are related to Nebivolol’s beta-adrenergic blocking activity. Among the most serious adverse effects are heart failure, heart block, and bronchospasm. Troublesome subjective side-effects include fatigue and coldness of the extremities. Reactions may be more severe following intravenous than oral administration; ocular use has also been associated with systemic adverse effects. When beta blockers are used for long-term treatment of asymptomatic diseases such as hypertension, subjective side-effects may be an important determinant of patient compliance.

The most common adverse effects of Amlodipine are associated with its vasodilator action and often diminish on continued therapy. They include dizziness, flushing, headache, hypotension, peripheral oedema, tachycardia, and palpitations. Nausea and other gastrointestinal disturbances, increased micturition frequency, lethargy, eye pain, visual disturbances, and mental depression have also occurred. A paradoxical increase in ischaemic chest pain may occur at the start of treatment and in a few patients excessive fall in blood pressure has led to cerebral or myocardial ischaemia or transient blindness.



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