EXFORGE 5/160/12.5 HCT (AMLODIPINE 5MG/VALSARTAN 160MG/HCTZ 12.5MG) – 28 TABLETS are used in the management of Hypertension/High Blood Pressure in Kenya. This is a condition characterized by a raise in blood pressure to levels of above 140/90mmHG. This product should not be used in pregnancy, unless with proper guidance from a qualified physician. You can buy it online in Kenya through ePharmacy Kenya Online Chemist.

SKU: EP1175 Category:


This specific brand/formulation of Valsartan contains Hydrochlorothiazide and Amlodipine. For details about their roles in controlling blood pressure, please search for their single ingredient formulation on ePharmacy Kenya Online Drug Store, by entering “HCTZ” or “Amlodipine” into the search bar.

Uses and Administration of Valsartan in Antihypertensive in Kenya

Valsartan is an angiotensin II receptor antagonist with actions similar to those of losartan. It is used in the management of hypertension and may also be used in patients with heart failure who are unable to tolerate the side effects of Angiotension-Converting Enzyme inhibitors. Valsartan is given by mouth. After an oral dose the hypotensive effect occurs within 2 hours, reaches a peak within 4 to 6 hours, and persists for over 24 hours. The maximum hypotensive effect is achieved within 2 to 4 weeks. In hypertension, valsartan is given in an initial dose of 80 mg once daily. This may be increased, if necessary, to 160 mg once daily, although doses of up to 320 mg once daily have been used in Kenya for severe cases. A lower initial dose of 40 mg once daily may be used in elderly patients over 75 years, and in those with intravascular volume depletion; similar dosage reductions have been suggested in renal or hepatic impairment. In heart failure, valsartan is given in an initial dose of 40 mg twice daily. The dose should be increased, as tolerated, to 160 mg twice daily.

Adverse Effects/Side Effects of Valsartan in Kenya

Adverse effects of Valsartan have been reported to be usually mild and transient, and include dizziness, headache, and dose-related orthostatic hypotension. Hypotension may occur particularly in patients with volume depletion (for example those who have received high-dose diuretics). Impaired renal function and, rarely, rash, urticaria, pruritus, angioedema, and raised liver enzyme values may occur. Hyperkalaemia, myalgia, and arthralgia have been reported. Other adverse effects of Valsartan that have been reported in Kenya include respiratory-tract disorders, back pain, gastrointestinal disturbances, fatigue, and neutropenia.

Valsartan should be used with caution in patients with hepatic impairment, cirrhosis, or biliary obstruction.

Interactions of Valsartan!!

Increased mortality/death has been reported with valsartan in patients with heart failure also receiving both ACE inhibitors and beta blockers and it should not be used in such patients in Kenya.


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