CO-ARINATE ADULT TABS 3’S

**Arinate Artesunate, Sulphamethoxypyrazine, Pyrimethamine** is a combination medication primarily used for the treatment of malaria. Artesunate is an antimalarial drug derived from artemisinin, effective against Plasmodium falciparum, the most severe malaria-causing parasite. It works by inhibiting the parasite’s ability to detoxify heme, leading to its death.

Sulphamethoxypyrazine is a sulfonamide antibiotic that enhances the efficacy of artesunate by providing additional antimicrobial action, particularly against certain bacterial infections that may co-occur with malaria.

Pyrimethamine is an antiparasitic agent that inhibits dihydrofolate reductase, crucial for the synthesis of folate in parasites, thus further aiding in the treatment of malaria.

This combination is particularly useful in areas with high resistance to other antimalarial drugs, providing a comprehensive approach to treating malaria and preventing complications associated with the disease.